So, a pet peeve of mine is when people send an email with no subject. I tried
to create a rule saying if the subject is blank/null, and it didn't work so
well, it wouldn't accept "" (for blank/null) as subject. Is there a way to do
this as a rule?

I'm wondering if there is something I could code in VBA (I'm sure there is)
where it will run (like a rule) and if the subject is blank/null it would
send (reply-all) a nice little email saying your email has not been read and
has been deleted, if your message is important please resubmit your email
with a proper subject header.

Is this possible? Or will I always have to was the few seconds of my life
hitting ctrl-q, ctrl-d (sending no reply at all)?